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Geraldine Hamilton: Body parts on a chip

Geraldine Hamilton: Body parts on a chip

 

 

It’s relatively easy to imagine a new medicine, a better cure for some disease. The hard part, though, is testing it, and that can delay promising new cures for years. In this well-explained talk, Geraldine Hamilton shows how her lab creates organs and body parts on a chip, simple structures with all the pieces essential to testing new medications — even custom cures for one specific person. (Filmed at TEDxBoston)

Geraldine Hamilton builds organs and body parts on a chip — to test new, custom cures.

 

WHY YOU SHOULD LISTEN TO HER?

 

Geraldine Hamilton’s career spans from academic research to biotech start-ups to pharma. Her research focus has been on the development and application of human-relevant in-vitro models for drug discovery. She was one of the founding scientists, VP of Scientific Operations and Director of Cell Products, in a start-up biotech company (CellzDirect), that successfully translated and commercialized technology from academic research to supply the pharmaceutical industry with hepatic cell products and services for safety assessment and drug-metabolism studies.

 

Hamilton received her Ph.D. in cell biology/toxicology from the University of Hertfordshire (England) in conjunction with GlaxoSmithkline, followed by a post-doctoral research fellowship at the University of North Carolina. Her current research interests and prior experience include: organs on-a-chip, toxicology and drug metabolism, liver cell biology, mechanisms regulating gene expression and differentiation, regulation of nuclear receptors and transcriptional activation in hepatocytes by xenobiotics, human cell isolation and cryopreservation techniques.

Elucidate: Method of recording brain activity could lead to mind-reading devices

neurosciencestuff:

A brain region activated when people are asked to perform mathematical calculations in an experimental setting is similarly activated when they use numbers — or even imprecise quantitative terms, such as “more than”— in everyday conversation, according to a study by…

Elucidate: Method of recording brain activity could lead to mind-reading devices

 

Kelly McGonigal: How to make stress your friend

Kelly McGonigal: How to make stress your friend

 

 

Stress. It makes your heart pound, your breathing quicken and your forehead sweat. But while stress has been made into a public health enemy, new research suggests that stress may only be bad for you if you believe that to be the case. Psychologist Kelly McGonigal urges us to see stress as a positive, and introduces us to an unsung mechanism for stress reduction: reaching out to others.

Kelly McGonigal translates academic research into practical strategies for health, happiness and personal success.

WHY YOU SHOULD LISTEN TO HER?

Stanford University psychologist Kelly McGonigal is a leader in the growing field of “science-help.” Through books, articles, courses and workshops, McGonigal works to help us understand and implement the latest scientific findings in psychology, neuroscience and medicine.

Straddling the worlds of research and practice, McGonigal holds positions in both the Stanford Graduate School of Business and the School of Medicine. Her most recent book, The Willpower Instinct, explores the latest research on motivation, temptation and procrastination, as well as what it takes to transform habits, persevere at challenges and make a successful change.

She is now researching a new book about the “upside of stress,” which will look at both why stress is good for us, and what makes us good at stress. In her words: “The old understanding of stress as a unhelpful relic of our animal instincts is being replaced by the understanding that stress actually makes us socially smart — it’s what allows us to be fully human.”

 

An Interview with Giuseppe Santoni of Santoni Footwear

An Interview with Giuseppe Santoni of Santoni Footwear

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Forbes Style Director Joseph DeAcetis interviews Guiseppe Santoni, CEO of Italian Luxury and Eco Friendly Footwear brand Santoni.

3 Dimensions of Innovation: James Wallbank

3 Dimensions of Innovation: James Wallbank

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In the late 90’s James imagined an alternative model of lifelong digital engagement that would be free and open to all, and would develop a wide range of skills and abilities at a minimal cost. A key seemed to be mobilising the wasted resources he saw around him – prematurely obsolete technology, trashed materials, empty buildings, and the wasted time of people who couldn’t find work.

The do-it-yourself media lab that emerged from that vision, Access Space, opened in 2000 and is still running today. It combines recycled computers, free software and the collective intelligence of a peer learning community to build a powerful platform for developing skills and enterprise. Access Space develops confidence, capability, creativity and connections, and seeks to spread its holistic approach.

Currently the organisation is researching the individual, enterprise and community development potential of advanced manufacturing technologies. James contends that access to technology and technological skills, are necessary, but insufficient, for individuals, enterprises or communities to thrive; other very different capabilities are also needed.

The Golden Era of Stem Cell Discoveries: Una Riekstina

The Golden Era of Stem Cell Discoveries: Una Riekstina

Una Riekstina is dedicating her life in the stem cell research. She got her PhD at Karolinska Institutet, in Stockholm. Currently she is Asoc. Professor and leading researcher at the Faculty of Medicine of University of Latvia. Una is a coauthor of 17 international research articles and 12 local research and popular science articles. She is a recipient of prestigious L’Oréal Latvia grant for Women in Science in year 2010. In her speech Una explains that adult stem cells are our body’s natural resource that renews the body lifelong. Stem cell research helps to find out ways how to use stem cells to cure diseases like heart attack, diabetes, lost vision and autoimmune diseases. Adult stem cells are the medicines of tomorrow that will improve the quality of life for many people yet they are not the panacea for all diseases.

 

Sniffing out schizophrenia using nose cell samples

Sniffing out schizophrenia using nose cell samples

June 26 – The human nose may hold the key to diagnosing schizophrenia, according to a team of US-Israeli researchers. They say that biological markers for the disease exist in nerve cells from the upper nasal cavity near the brain, a discovery that could lead to biological diagnosis for schizophrenia and the development of drugs to treat it.

 

Toward a new understanding of mental illness – Thomas Insel

Toward a new understanding of mental illness – Thomas Insel

Today, thanks to better early detection, there are 63% fewer deaths from heart disease than there were just a few decades ago. Thomas Insel, Director of the National Institute of Mental Health, wonders: Could we do the same for depression and schizophrenia? The first step in this new avenue of research, he says, is a crucial reframing.

 

The Myth of Average: Todd Rose

The Myth of Average: Todd Rose

High school dropout turned Harvard faculty talks about how a simple new way of thinking helps nurture individual potential.

L. Todd Rose is co-founder and president of Project Variability, an organization dedicated to providing leadership around the emerging new science of the individual and its implications for education, the workforce, and society. In addition, he is a faculty member at the Harvard Graduate School of Education, where he teaches Educational Neuroscience. Todd is also the author of Square Peg: My story and what it means for raising visionaries, innovators, and out-of-the-box thinkers.

 

Smiling Can Save Your Life: Lisa Sparks

Smiling Can Save Your Life: Lisa Sparks

Lisa Sparks, Ph.D., is a highly regarded teacher-scholar whose published work includes more than 100 research articles and scholarly book chapters. She is also the author and editor of more than ten books in the areas of communication, health, and aging.

Sparks is the Foster and Mary McGaw Endowed Professor in Behavioral Sciences at Chapman University and directs the Master of Science graduate program in Health and Strategic Communication at the university. She also serves as a member of the Chao Family/NCl Designated Comprehensive Cancer Center at the University of California, Irvine, and Adjunct Professor in the Department of Population Health and Disease Prevention, Program in Public Health. Her research goal is to understand and create evidence-based health messages that effectively change health behavior resulting in better health outcomes.

Prior to joining Chapman in 2006, Sparks occupied faculty positions at George Mason University and the University of Texas at San Antonio.