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Christine Lagarde’s Advice To Women: Grit Your Teeth & Smile
IMF chief on economic empowerment, gender roles in leadership and insights for young career women.
How to Become a Culture-Changer: Evan Grae Davis
Husband, father, adventurer, activist; Evan Grae Davis has traveled the world with camera in hand for nearly two decades advocating for social justice through writing and directing short documentaries and educational videos championing the cause of the poor and exploited.
Evan recently released his first feature length documentary film asking why nearly 200 million women are missing in the world today– killed, aborted and abandoned simply because they are girls.
It’s a Girl is currently screening in hundreds of locations around the world, including colleges and universities, film festivals, at the European and British Parliaments and, recently, on Capitol Hill in Washington DC. With nearly half a million people joining the cause to end gendercide so far as a result of his film, Evan is on a mission to mobilize a movement to restore dignity and value to the girls of India and China.
The rates of regional brain loss and cognitive decline caused by aging and the early stages of Alzheimer’s disease (AD) are higher for women and for people with a key genetic risk factor for AD, say researchers at the University of California, San Diego School of Medicine in a study published online July 4 in the American Journal of Neuroradiology.
The linkage between APOE ε4 – which codes for a protein involved in binding lipids or fats in the lymphatic and circulatory systems – was already documented as the strongest known genetic risk factor for sporadic AD, the most common form of the disease. But the connection between the sex of a person and AD has been less-well recognized, according to the UC San Diego scientists.
“APOE ε4 has been known to lower the age of onset and increase the risk of getting the disease,” said the study’s first author Dominic Holland, PhD, a researcher in the Department of Neurosciences at UC San Diego School of Medicine. “Previously we showed that the lower the age, the higher the rates of decline in AD. So it was important to examine the differential effects of age and APOE ε4 on rates of decline, and to do this across the diagnostic spectrum for multiple clinical measures and brain regions, which had not been done before.”
The scientists evaluated 688 men and women over the age of 65 participating in the Alzheimer’s Disease Neuroimaging Initiative, a longitudinal, multi-institution study to track the progression of AD and its effects upon the structures and functions of the brain. They found that women with mild cognitive impairment (a condition precursory to AD diagnosis) experienced higher rates of cognitive decline than men; and that all women, regardless of whether or not they showed signs of dementia, experienced greater regional brain loss over time than did men. The magnitude of the sex effect was as large as that of the APOE ε4 allele.
“Assuming larger population-based samples reflect the higher rates of decline for women than men, the question becomes what is so different about women,” said Holland. Hormonal differences or change seems an obvious place to start, but Holland said this is largely unknown territory – at least regarding AD.
“Another important finding of this study is that men and women did not differ in the level of biomarkers of Alzheimer’s disease pathology,” said co-author Linda McEvoy, PhD, an associate professor in the UCSD Department of Radiology. “This suggests that brain volume loss in women may also be caused by factors other than Alzheimer’s disease, or that in women, these pathologies are more toxic. We clearly need more research on how an individual’s sex affects AD pathogenesis.”
Holland acknowledged that the paper likely raises more questions than it answers. “There are many factors that may affect the sex differences we observed, such as whether the women in this study may have had higher rates of diabetes or insulin resistance than the men. We also do not know how the use of hormone replacement therapy, reproductive history or years since menopause may have affected these differences. All these issues need to be examined. There is no prevailing theory.”
Cisco CTO and Forbes power woman Padmasree Warrior on gender, technology and power in the workplace.
The One Question – Christine Louise Hohlbaum
Warren Buffet & Tony Robbins speak on the journey to success
Warren Buffet and Tony Robbins sit alongside some of today’s greatest minds in several veracious financial and motivational industries to discuss what it takes to make it in society today. There are several great motivational quotes that all entrepreneurs can apply on the journey to success.
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Living A Family Philanthropic Legacy: Conversation with Anne Springs Close
Moderated by: Virginia Esposito, President of the National Center for Family Philanthropy
An intimate conversation with Mrs. Anne Springs Close, Chairman of The Springs Close Foundation, who will share her experiences, challenges, surprises, and lessons learned in philanthropy. This conversation will inspire philanthropists who shape the social sector and work to leave behind similar legacies of charitable success and generosity.
The Supreme Sacrifice
One woman’s motivation to achieve was based on a tragic childhood memory.
Sheryl Sandberg’s advice for men
Facebook COO Sheryl Sandberg talks to Fortune Senior Editor-At-Large Pattie Sellers about her book ‘Lean In’ and her advice for men in the workplace.
Oprah Winfrey Is World s Most Powerful Celeb for the Fifth Time
Oprah has done it again. She is the world s most powerful celeb, according to Forbes.
Women and Money: Patricia Annino
Women have control of more personal wealth than ever before, yet many women do not take the steps necessary to protect that wealth for themselves and their families. Attorney and author Patricia Annino discusses the biggest planning challenges facing women today, and the most important steps a woman can take to plan for her financial future. Ms. Annino is interviewed by Donald Levitt, Ph.D.
Prospecting and Philanthropic Planning
Author Margaret May Damen, CLU®, ChFC®, CFP®, Founder and President of the Institute for Women and Wealth and two faculty members from The American College discuss who the most likely prospects for philanthropic planning services are and how to find them.
Women Leadership: The Ethic of Self Empowerment: Chiara Palieri
Pramodita Sharma: Research on Women in Family Business
Pramodita Sharma describes recent research trends regarding women in family business. She notes which trends are most relevant to women currently working in a family business, and she describes promising areas for future research.